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High-resolution, large-scale mosaic image for a full coronal mouse tissue showing global views of different brain regions, as well as cellular and subcellular details, identified distinct localization of PKA RIβ and RIIβ regulatory subunits. Triple labeled for Nuclei (Hoescht stain, blue), RIβ (cy3, red) and RIIβ (Alexa 488, green). This image is a maximum projection of the Z-stack through the tissue, and has been downsampled from the raw data image, which can be accessed using the link provided to the Cell Image Library.

High-resolution montage of a sagittal section through the cerebellar cortex of an adult male mouse, triple labeled for Nuclei (Hoescht stain, blue), RIβ (cy3, red) and RIIβ (Alexa 488, green). This image is a maximum projection of the Z-stack through the tissue, and has been downsampled from the raw data image, which can be accessed using the link provided to the Cell Image Library.

High-resolution, large-scale mosaic image, for mouse brain coronal section through the dorsal hippocampus, identified distinct localization of PKA RIβ and RIIβ regulatory subunits across various hippocampal subfields. Triple labeled for Nuclei (Hoescht stain, blue), RIβ (cy3, red) and RIIβ (Alexa 488, green). This image is a maximum projection of the Z-stack through the tissue, and has been downsampled from the raw data image, which can be accessed using the link provided to the Cell Image Library.

Atomic coordinates for RIb holenzyme structure in the Protein Data Bank (PDB ID 4DIN).

Structural summary at the National Center for biotechnology information (NCBI)